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Scientific article
English

Serotonin syndrome after concomitant treatment with linezolid and citalopram

Published inClinical infectious diseases, vol. 36, no. 9, 1197
Publication date2003
Abstract

Linezolid, a new synthetic antimicrobial, is an important weapon against methicillin-resistant Staphylococcus aureus (MRSA). Although there are reports of serotonin syndrome developing after concomitant use of linezolid and the selective serotonin reuptake inhibitor paroxitene, this report concerns a patient receiving citalopram who developed thrombocytopenia, serotonin syndrome, and lactic acidosis and died following long-term linezolid therapy.

Keywords
  • Acetamides/ adverse effects
  • Acidosis, Lactic/chemically induced
  • Citalopram/ adverse effects
  • Drug Combinations
  • Humans
  • Oxazolidinones/ adverse effects
  • Protein Synthesis Inhibitors/adverse effects
  • Serotonin Syndrome/ chemically induced
  • Serotonin Uptake Inhibitors/adverse effects
  • Staphylococcus aureus/drug effects
  • Thrombocytopenia/chemically induced
Citation (ISO format)
BERNARD, Louis et al. Serotonin syndrome after concomitant treatment with linezolid and citalopram. In: Clinical infectious diseases, 2003, vol. 36, n° 9, p. 1197. doi: 10.1086/374558
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accessLevelRestricted
Identifiers
ISSN of the journal1058-4838
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