Oxindole synthesis by direct coupling of C(sp2)-H and C(sp3)-H Centers

Jia, Yixia; Kundig, Ernst Peter

doi:10.1002/anie.200805652

Scientific article

English

Oxindole synthesis by direct coupling of C(sp2)-H and C(sp3)-H Centers

ContributorsJia, Yixia; Kundig, Ernst Peter

Published inAngewandte Chemie, vol. 48, no. 9, p. 1636-1639

Publication date2009

Abstract

An sp2/sp3 get-together: A novel and efficient method can be used to synthesize 3,3-disubstitued oxindoles by the direct intramolecular oxidative coupling of an aryl Csp2—H and a Csp3—H center (see scheme, DMF=N,N-dimethylformamide).

Affiliation entities

Faculté des sciences / Section de chimie et biochimie / Département de chimie organique

Citation (ISO format)

JIA, Yixia, KUNDIG, Ernst Peter. Oxindole synthesis by direct coupling of C(sp2)-H and C(sp3)-H Centers. In: Angewandte Chemie, 2009, vol. 48, n° 9, p. 1636–1639. doi: 10.1002/anie.200805652

Article

Identifiers

PID : unige:7026
DOI : 10.1002/anie.200805652
PMID : 19170152

Journal ISSN1433-7851

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Oxindole synthesis by direct coupling of C(sp2)-H and C(sp3)-H Centers

An sp2/sp3 get-together: A novel and efficient method can be used to synthesize 3,3-disubstitued oxindoles by the direct intramolecular oxidative coupling of an aryl Csp2—H and a Csp3—H center (see scheme, DMF=N,N-dimethylformamide).

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