en
Scientific article
Letter
English

Voltage-Dependent Ion Channel Formation by Rigid Rod-Shaped Polyols in Planar Lipid Bilayers

Published inBioorganic & medicinal chemistry letters, vol. 8, no. 19, p. 2743-2746
Publication date1998
Abstract

In this Letter, we describe the appearance of large, voltage-dependent currents in BLM induced by rigid rodshaped polyols that function without charge and permanent dipole moment. The capacity of these symmetrical, nonpeptide models to form either short-living nanopores or small ion channels is shown to depend critically on the length of rigid-rod scaffold as well as the nature of the lateral side chains.

Affiliation Not a UNIGE publication
Citation (ISO format)
SAKAI, Naomi et al. Voltage-Dependent Ion Channel Formation by Rigid Rod-Shaped Polyols in Planar Lipid Bilayers. In: Bioorganic & medicinal chemistry letters, 1998, vol. 8, n° 19, p. 2743–2746. doi: 10.1016/S0960-894X(98)00481-8
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ISSN of the journal0960-894X
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