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Scientific article
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En Route to Supramolecular Functional Plasticity: Synthetic β-Barrels, the Barrel-Stave Motif, and Related Approaches

ContributorsMatile, Stefan
Published inChemical Society reviews, vol. 30, p. 158-167
Publication date2001
Abstract

This review emphasizes recent or pertinent efforts to create functional plasticity with artificial barrel-stave supramolecules and related motifs. On the structural level, a summary of engineered, de novo designed, and artificial ß-barrels beyond peptide chemistry is followed by representative a-helix bundles and barrel-stave supramolecules comprising oligonucleotides, inorganic architecture, and organic barrel-stave ion channel models. On the functional level, selected examples are given to highlight divers aspects of molecular recognition, translocation, and transformation that are currently accessible with artificial barrel-stave supramolecules.

Citation (ISO format)
MATILE, Stefan. En Route to Supramolecular Functional Plasticity: Synthetic β-Barrels, the Barrel-Stave Motif, and Related Approaches. In: Chemical Society reviews, 2001, vol. 30, p. 158–167. doi: 10.1039/b008101i
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