Amphotericin B as a Potential Probe of the Physical State of Vesicle Membranes

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Title		Amphotericin B as a Potential Probe of the Physical State of Vesicle Membranes
Authors		Zumbuehl, Andréas Stano, Pasquale Heer, Dominik Walde, Peter Carreira, Erick M.
Published in		Organic Letters. 2004, vol. 6, no. 21, p. 3683-3686
Abstract		The investigations described introduce a new role for a natural product such as amphotericin B as a potential biophysical reporter group to probe the physical state of a membrane. Specifically, we demonstrated that the K(+) efflux pattern reveals an interesting sterol dependence. This is suggested to be correlated to the physical state of the membrane showing high efflux in a vesicle membrane of intermediate fluidity.
Identifiers		DOI: 10.1021/ol0487276 PMID: 15469323
Full text		Article - Limited access to UNIGE
Citation (ISO format)		ZUMBUEHL, Andréas et al. Amphotericin B as a Potential Probe of the Physical State of Vesicle Membranes. In: Organic Letters, 2004, vol. 6, n° 21, p. 3683-3686. https://archive-ouverte.unige.ch/unige:6961