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Title

Amphotericin B as a Potential Probe of the Physical State of Vesicle Membranes

Authors
Stano, Pasquale
Heer, Dominik
Walde, Peter
Carreira, Erick M.
Published in Organic Letters. 2004, vol. 6, no. 21, p. 3683-3686
Abstract The investigations described introduce a new role for a natural product such as amphotericin B as a potential biophysical reporter group to probe the physical state of a membrane. Specifically, we demonstrated that the K(+) efflux pattern reveals an interesting sterol dependence. This is suggested to be correlated to the physical state of the membrane showing high efflux in a vesicle membrane of intermediate fluidity.
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PMID: 15469323
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ZUMBUEHL, Andréas et al. Amphotericin B as a Potential Probe of the Physical State of Vesicle Membranes. In: Organic Letters, 2004, vol. 6, n° 21, p. 3683-3686. https://archive-ouverte.unige.ch/unige:6961

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Deposited on : 2010-06-18

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