Scientific article
Letter
English

Amphotericin B as a Potential Probe of the Physical State of Vesicle Membranes

Published inOrganic letters, vol. 6, no. 21, p. 3683-3686
Publication date2004
Abstract

The investigations described introduce a new role for a natural product such as amphotericin B as a potential biophysical reporter group to probe the physical state of a membrane. Specifically, we demonstrated that the K(+) efflux pattern reveals an interesting sterol dependence. This is suggested to be correlated to the physical state of the membrane showing high efflux in a vesicle membrane of intermediate fluidity.

Affiliation entities Not a UNIGE publication
Citation (ISO format)
ZUMBUEHL, Andréas et al. Amphotericin B as a Potential Probe of the Physical State of Vesicle Membranes. In: Organic letters, 2004, vol. 6, n° 21, p. 3683–3686. doi: 10.1021/ol0487276
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Journal ISSN1523-7052
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