Rapid Access to Synthetic Lysobisphosphatidic Acids Using PIII Chemistry

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Title		Rapid Access to Synthetic Lysobisphosphatidic Acids Using PIII Chemistry
Authors		Chevallier, Julien Sakai, Naomi Robert, Fabien Kobayashi, Toshihide Gruenberg, Jean Matile, Stefan
Published in		Organic Letters. 2000, vol. 2, no. 13, p. 1859-1861
Abstract		An expeditious route to synthetic lysobisphosphatidic acid S,S-1, its enantiomer, and regioisomers is reported. Synthetic difficulties concerning lipid stability and stereochemistry are bypassed using a phosphite triester approach in combination with multiple silyl protection. Spectroscopic studies evidence that acyl group migration in S,S-1 is accelerated by nonpolar solvents and inhibited by pyridine.
Identifiers		DOI: 10.1021/ol0059246 PMID: 10891176
Full text		Article - Limited access to UNIGE
Structures		Faculté des sciences / Section de chimie et biochimie / Département de chimie organique
Citation (ISO format)		CHEVALLIER, Julien et al. Rapid Access to Synthetic Lysobisphosphatidic Acids Using PIII Chemistry. In: Organic Letters, 2000, vol. 2, n° 13, p. 1859-1861. doi: 10.1021/ol0059246 https://archive-ouverte.unige.ch/unige:6954