We report the completion of a series of biological ß-barrel pores blocked by an agr-helix (Oomen et al., EMBO J. 2004, 23, 1257) and rigid-rod ß-barrel pores blocked by an a-helix (Sordé and Matile, J. Supramol. Chem. 2002, 2, 191) with experimental evidence for a rigid-rod ß-barrel pore blocked by a rigid-rod a-helix mimic. These presumably dimeric, shape-persistent p-oligophenyl a-helix mimics are of interest to address the functional-group density of full a-helix surfaces and to obtain insights into a-helix folding and recognition.