Scientific article

Blockage of Rigid-Rod β-Barrel Pores by Rigid-Rod α-Helix Mimics

Published inSupramolecular chemistry, vol. 17, no. 1-2, p. 135-139
Publication date2005

We report the completion of a series of biological ß-barrel pores blocked by an agr-helix (Oomen et al., EMBO J. 2004, 23, 1257) and rigid-rod ß-barrel pores blocked by an a-helix (Sordé and Matile, J. Supramol. Chem. 2002, 2, 191) with experimental evidence for a rigid-rod ß-barrel pore blocked by a rigid-rod a-helix mimic. These presumably dimeric, shape-persistent p-oligophenyl a-helix mimics are of interest to address the functional-group density of full a-helix surfaces and to obtain insights into a-helix folding and recognition.

  • Barrel-stave supramolecules
  • Lipid bilayer membranes
  • Molecular recognition
  • Self-assembly
  • Synthetic multifunctional pores
Citation (ISO format)
LITVINCHUK, Svetlana, MATILE, Stefan. Blockage of Rigid-Rod β-Barrel Pores by Rigid-Rod α-Helix Mimics. In: Supramolecular chemistry, 2005, vol. 17, n° 1-2, p. 135–139. doi: 10.1080/10610270412331328952
ISSN of the journal1026-7816

Technical informations

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