Scientific article

Viruses and endosome membrane dynamics

ContributorsGruenberg, Jean
Published inCurrent opinion in cell biology, vol. 21, no. 4, p. 582-588
Publication date2009

Cell surface molecules, ligands, and solutes can be endocytosed into animal cells via several pathways in addition to clathrin-mediated endocytosis, which all seem to lead to canonical endosomes. It seems that viruses can enter and infect cells through most of, if not all, endocytic routes, having evolved different, sometimes elaborate, strategies to (mis)use cellular machineries to their own benefit during infection. In this short review, I will discuss recent progress in understanding the pathways followed by animal viruses into cells, and how these studies are also providing novel insights into our understanding of some molecular mechanisms that control endocytic membrane transport.

  • Animals
  • Calcium-Binding Proteins/metabolism
  • Cell Cycle Proteins/metabolism
  • Cell Membrane/virology
  • Cytosol/metabolism
  • DNA-Binding Proteins/metabolism
  • Endocytosis
  • Endosomal Sorting Complexes Required for Transport/metabolism
  • Endosomes/metabolism
  • Humans
  • Hydrogen-Ion Concentration
  • Ligands
  • Models, Biological
  • Transcription Factors/metabolism
  • Vesiculovirus/metabolism
  • Virus Internalization
  • Viruses/metabolism
Citation (ISO format)
GRUENBERG, Jean. Viruses and endosome membrane dynamics. In: Current opinion in cell biology, 2009, vol. 21, n° 4, p. 582–588. doi: 10.1016/j.ceb.2009.03.008
Main files (1)
Article (Published version)
ISSN of the journal0955-0674

Technical informations

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