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Viruses and endosome membrane dynamics

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Published in Current Opinion in Cell Biology. 2009, vol. 21, no. 4, p. 582-8
Abstract Cell surface molecules, ligands, and solutes can be endocytosed into animal cells via several pathways in addition to clathrin-mediated endocytosis, which all seem to lead to canonical endosomes. It seems that viruses can enter and infect cells through most of, if not all, endocytic routes, having evolved different, sometimes elaborate, strategies to (mis)use cellular machineries to their own benefit during infection. In this short review, I will discuss recent progress in understanding the pathways followed by animal viruses into cells, and how these studies are also providing novel insights into our understanding of some molecular mechanisms that control endocytic membrane transport.
Keywords AnimalsCalcium-Binding Proteins/metabolismCell Cycle Proteins/metabolismCell Membrane/virologyCytosol/metabolismDNA-Binding Proteins/metabolismEndocytosisEndosomal Sorting Complexes Required for Transport/metabolismEndosomes/metabolismHumansHydrogen-Ion ConcentrationLigandsModels, BiologicalTranscription Factors/metabolismVesiculovirus/metabolismVirus InternalizationViruses/metabolism
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PMID: 19443190
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GRUENBERG, Jean. Viruses and endosome membrane dynamics. In: Current Opinion in Cell Biology, 2009, vol. 21, n° 4, p. 582-8. https://archive-ouverte.unige.ch/unige:5666

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Deposited on : 2010-03-31

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