UNIGE document Scientific Article
previous document  unige:55978  next document
add to browser collection

Role of endogenous histamine in altered lung mechanics in rabbits

Published in Anesthesiology. 2002, vol. 96, no. 2, p. 409-15
Abstract Unlike the effects of exogenous histamine, those of endogenous histamine on the lung mechanics have not yet been characterized. The site of endogenous histamine liberation by mivacurium was determined, as were the effects of this histamine on the airway and parenchymal mechanics in control rabbits (group C) and rabbits pretreated with H1 and H2 receptor blockers (group AH). The effectiveness of the receptor blockade was ensured by challenges with exogenous histamine.
Keywords Airway Resistance/drug effects/physiologyAlgorithmsAnimalsBlood Pressure/drug effectsHistamine/blood/pharmacology/physiologyHistamine Antagonists/pharmacologyIsoquinolines/pharmacologyLung/drug effects/physiologyMaleModels, BiologicalNeuromuscular Nondepolarizing Agents/pharmacologyPulmonary Circulation/drug effectsRabbitsRespiratory Mechanics/drug effects/physiology
PMID: 11818775
Full text
Research group Enfants et hyperréactivité bronchique (69)
(ISO format)
HABRE, Walid et al. Role of endogenous histamine in altered lung mechanics in rabbits. In: Anesthesiology, 2002, vol. 96, n° 2, p. 409-15. https://archive-ouverte.unige.ch/unige:55978

415 hits



Deposited on : 2015-04-30

Export document
Format :
Citation style :