Chronic inhibition of circulating dipeptidyl peptidase IV by FE 999011 delays the occurrence of diabetes in male zucker diabetic fatty rats
Published inDiabetes, vol. 51, no. 5, p. 1461-1469
Publication date2002
Abstract
Keywords
- Animals
- Blood Glucose
- Diabetes Mellitus/blood/drug therapy/enzymology
- Diabetes Mellitus, Type 2/blood/drug therapy
- Dipeptidyl Peptidase 4/blood
- Drinking/drug effects
- Eating/drug effects
- Fatty Acids, Nonesterified/blood
- Gene Expression/physiology
- Glucagon/blood
- Glucagon-Like Peptide 1
- Glucose Tolerance Test
- Humans
- Insulin/blood
- Male
- Nitriles/chemistry/pharmacology
- Obesity
- Pancreas/physiology
- Peptide Fragments/blood
- Protease Inhibitors/chemistry/pharmacology
- Protein Precursors/blood
- Pyrrolidines/chemistry/pharmacology
- Rats
- Rats, Zucker
- Receptors, Glucagon/genetics
- Triglycerides/blood
- Weight Gain/drug effects
Citation (ISO format)
SUDRE, Béatrice et al. Chronic inhibition of circulating dipeptidyl peptidase IV by FE 999011 delays the occurrence of diabetes in male zucker diabetic fatty rats. In: Diabetes, 2002, vol. 51, n° 5, p. 1461–1469. doi: 10.2337/diabetes.51.5.1461
Main files (1)
Article (Published version)
Identifiers
- PID : unige:55899
- DOI : 10.2337/diabetes.51.5.1461
- PMID : 11978643
ISSN of the journal0012-1797