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Title

Ganciclovir for severe cytomegalovirus primary infection in an immunocompetent child

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Published in European Journal of Clinical Microbiology & Infectious Diseases. 2004, vol. 23, no. 3, p. 218-20
Abstract Described here is the unusual case of a previously healthy 17-month-old girl who developed severe cytomegalovirus (CMV) disease with prolonged fever and hepatitis. The severity of her illness required hospitalization and prompted antiviral treatment. Short-term intravenous ganciclovir treatment was associated with immediate and sustained resolution of the symptoms as well as a sharp decrease of CMV viremia. This observation suggests that antiviral therapy might be considered in select cases of severe primary CMV infection in immunocompetent children.
Keywords Cytomegalovirus/isolation & purificationCytomegalovirus Infections/diagnosis/drug therapy/immunologyDose-Response Relationship, DrugDrug Administration ScheduleFemaleFollow-Up StudiesGanciclovir/administration & dosageHumansImmunocompetenceInfantInfusions, IntravenousRisk AssessmentSeverity of Illness IndexTreatment Outcome
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PMID: 14767679
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Research group Etiologie des pneumonies et marqueurs inflammatoires chez l'enfant fébrile (183)
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HADAYA, Karine et al. Ganciclovir for severe cytomegalovirus primary infection in an immunocompetent child. In: European Journal of Clinical Microbiology & Infectious Diseases, 2004, vol. 23, n° 3, p. 218-20. https://archive-ouverte.unige.ch/unige:55540

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Deposited on : 2015-04-14

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