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Scientific article
Open access
English

Ganciclovir for severe cytomegalovirus primary infection in an immunocompetent child

Collection
  • Open Access - Licence nationale Springer
Publication date2004
Abstract

Described here is the unusual case of a previously healthy 17-month-old girl who developed severe cytomegalovirus (CMV) disease with prolonged fever and hepatitis. The severity of her illness required hospitalization and prompted antiviral treatment. Short-term intravenous ganciclovir treatment was associated with immediate and sustained resolution of the symptoms as well as a sharp decrease of CMV viremia. This observation suggests that antiviral therapy might be considered in select cases of severe primary CMV infection in immunocompetent children.

Keywords
  • Cytomegalovirus/isolation & purification
  • Cytomegalovirus Infections/diagnosis/drug therapy/immunology
  • Dose-Response Relationship, Drug
  • Drug Administration Schedule
  • Female
  • Follow-Up Studies
  • Ganciclovir/administration & dosage
  • Humans
  • Immunocompetence
  • Infant
  • Infusions, Intravenous
  • Risk Assessment
  • Severity of Illness Index
  • Treatment Outcome
Citation (ISO format)
HADAYA, Karine et al. Ganciclovir for severe cytomegalovirus primary infection in an immunocompetent child. In: European journal of clinical microbiology & infectious diseases, 2004, vol. 23, n° 3, p. 218–220. doi: 10.1007/s10096-003-1079-z
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Article (Published version)
accessLevelPublic
Identifiers
ISSN of the journal0934-9723
487views
185downloads

Technical informations

Creation2015/02/24 13:27:00
First validation2015/02/24 13:27:00
Update time2023/03/14 23:11:28
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