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Extra-osseous involvement of Langerhans' cell histiocytosis in children

Schmidt, Sabine
Eich, Georg
Tschäppeler, Heinz
Waibel, Peter
Gudinchet, François
Published in Pediatric Radiology. 2004, vol. 34, no. 4, p. 313-21
Abstract The predominant clinical and radiological features of Langerhans' cell histiocytosis (LCH) in children are due to osseous involvement. Extra-osseous disease is far less common, occurring in association with bone disease or in isolation; nearly all anatomical sites may be affected and in very various combinations. The following article is based on a multicentre review of 31 children with extra-osseous LCH. The objective is to summarise the diverse possibilities of organ involvement. The radiological manifestations using different imaging modalities are rarely pathognomonic on their own. Nevertheless, familiarity with the imaging findings, especially in children with systemic disease, may be essential for early diagnosis.
Keywords AdolescentAge DistributionCentral Nervous System Diseases/diagnosis/epidemiologyChildChild, PreschoolComorbidityConnective Tissue Diseases/diagnosis/epidemiologyDiagnostic Imaging/methodsDigestive System Diseases/diagnosis/epidemiologyFemaleHistiocytosis, Langerhans-Cell/diagnosis/epidemiologyHumansIncidenceInfantMalePrognosisRisk AssessmentSeverity of Illness IndexSex Distribution
PMID: 14740201
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Research group Radiologie neuro-diagnostique et neuro-interventionnelle en pédiatrie (842)
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SCHMIDT, Sabine et al. Extra-osseous involvement of Langerhans' cell histiocytosis in children. In: Pediatric Radiology, 2004, vol. 34, n° 4, p. 313-21. doi: 10.1007/s00247-003-1118-z https://archive-ouverte.unige.ch/unige:55481

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Deposited on : 2015-04-13

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