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Scientific article
English

Genetic deletion of the adaptor protein p66Shc increases susceptibility to short-term ischaemic myocardial injury via intracellular salvage pathways

Published inEuropean heart journal, vol. 36, no. 8, p. 516-526
Publication date2015
Abstract

Several intracellular mediators have been implicated as new therapeutic targets against myocardial ischaemia and reperfusion injury. However, clinically effective salvage pathways remain undiscovered. Here, we focused on the potential role of the adaptor protein p66(Shc) as a regulator of myocardial injury in a mouse model of cardiac ischaemia and reperfusion.

Citation (ISO format)
AKHMEDOV, Alexander et al. Genetic deletion of the adaptor protein p66Shc increases susceptibility to short-term ischaemic myocardial injury via intracellular salvage pathways. In: European heart journal, 2015, vol. 36, n° 8, p. 516–526. doi: 10.1093/eurheartj/ehu400
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ISSN of the journal0195-668X
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Creation03/02/2015 3:11:00 PM
First validation03/02/2015 3:11:00 PM
Update time03/14/2023 11:10:44 PM
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