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Clinical classification of pulmonary hypertension

Simonneau, Gerald
Galiè, Nazzareno
Rubin, Lewis J
Langleben, David
Seeger, Werner
Gibbs, Simon
Lebrec, Didier
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Published in Journal of the American College of Cardiology. 2004, vol. 43, no. 12 Suppl S, p. 5S-12S
Abstract In 1998, during the Second World Symposium on Pulmonary Hypertension (PH) held in Evian, France, a clinical classification of PH was proposed. The aim of the Evian classification was to individualize different categories sharing similarities in pathophysiological mechanisms, clinical presentation, and therapeutic options. The Evian classification is now well accepted and widely used in clinical practice, especially in specialized centers. In addition, this classification has been used by the U.S. Food and Drug Administration and the European Agency for Drug Evaluation for the labeling of newly approved medications in PH. In 2003, during the Third World Symposium on Pulmonary Arterial Hypertension held in Venice, Italy, it was decided to maintain the general architecture and philosophy of the Evian classification. However, some modifications have been proposed, mainly to abandon the term "primary pulmonary hypertension" and to replace it with "idiopathic pulmonary hypertension"; to reclassify pulmonary veno-occlusive disease and pulmonary capillary hemangiomatosis; to update risk factors and associated conditions for pulmonary arterial hypertension and to propose guidelines in order to improve the classification of congenital systemic-to-pulmonary shunts.
Keywords Genetic Predisposition to DiseaseHumansHypertension, Pulmonary/classification/diagnosis/epidemiologyPulmonary Veno-Occlusive Disease/classification/diagnosis/epidemiologyRisk Factors
PMID: 15194173
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Research group L'hypertension pulmonaire (pédiatrie) (228)
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SIMONNEAU, Gerald et al. Clinical classification of pulmonary hypertension. In: Journal of the American College of Cardiology, 2004, vol. 43, n° 12 Suppl S, p. 5S-12S. doi: 10.1016/j.jacc.2004.02.037 https://archive-ouverte.unige.ch/unige:55344

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Deposited on : 2015-04-09

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