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Fulminant liver failure in a child with invasive group A streptococcal infection

Published in European journal of pediatrics. 2003, vol. 162, no. 4, p. 245-7
Abstract Liver involvement is mentioned in streptococcal toxic shock syndrome, but never as fulminant liver failure (FLF). We report the case of a 2-year-old child who developed isolated FLF secondary to invasive group A streptococcal infection without shock due to a M1T1-type strain expressing speA, speB and speC toxin genes. On antibiotics, he recovered rapidly without liver transplantation.
Keywords Anti-Bacterial Agents/therapeutic useBacterial Toxins/biosynthesis/geneticsChild, PreschoolClindamycin/therapeutic useExotoxins/biosynthesis/geneticsHumansLiver Failure/drug therapy/microbiologyMalePenicillin G/therapeutic usePenicillins/therapeutic useStreptococcal Infections/complications/drug therapy/geneticsStreptococcus pyogenes/genetics/metabolism
PMID: 12647197
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Research groups Etiologie des pneumonies et marqueurs inflammatoires chez l'enfant fébrile (183)
Gastroentérologie et transplantation (pédiatrie) (181)
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BIESEL-DESTHIEUX, Marie-Noëlle Christine M. et al. Fulminant liver failure in a child with invasive group A streptococcal infection. In: European journal of pediatrics, 2003, vol. 162, n° 4, p. 245-7. doi: 10.1007/s00431-002-1137-z https://archive-ouverte.unige.ch/unige:55329

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Deposited on : 2015-04-09

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