Fulminant liver failure in a child with invasive group A streptococcal infection

Biesel-desthieux, Marie-Noëlle Christine M.; Tissières, Pierre; Belli, Dominique Charles; Le Coultre, Claude Pierrette; Gervaix, Alain; Masserey Spicher, Virginie

doi:10.1007/s00431-002-1137-z

Scientific article

Case report

English

Fulminant liver failure in a child with invasive group A streptococcal infection

ContributorsBiesel-desthieux, Marie-Noëlle Christine M.; Tissières, Pierre; Belli, Dominique Charles; Le Coultre, Claude Pierrette; Gervaix, Alain; Masserey Spicher, Virginie

Published inEuropean journal of pediatrics, vol. 162, no. 4, p. 245-247

Publication date2003

Abstract

Liver involvement is mentioned in streptococcal toxic shock syndrome, but never as fulminant liver failure (FLF). We report the case of a 2-year-old child who developed isolated FLF secondary to invasive group A streptococcal infection without shock due to a M1T1-type strain expressing speA, speB and speC toxin genes. On antibiotics, he recovered rapidly without liver transplantation.

Keywords

Anti-Bacterial Agents/therapeutic use
Bacterial Toxins/biosynthesis/genetics
Child, Preschool
Clindamycin/therapeutic use
Exotoxins/biosynthesis/genetics
Humans
Liver Failure/drug therapy/microbiology
Male
Penicillin G/therapeutic use
Penicillins/therapeutic use
Streptococcal Infections/complications/drug therapy/genetics
Streptococcus pyogenes/genetics/metabolism

Affiliation

Faculté de médecine / Section de médecine clinique / Département de pédiatrie, gynécologie et obstétrique

Research group

Citation (ISO format)

BIESEL-DESTHIEUX, Marie-Noëlle Christine M. et al. Fulminant liver failure in a child with invasive group A streptococcal infection. In: European journal of pediatrics, 2003, vol. 162, n° 4, p. 245–247. doi: 10.1007/s00431-002-1137-z

Article (Published version)

Identifiers

PID : unige:55329
DOI : 10.1007/s00431-002-1137-z
PMID : 12647197

ISSN of the journal0340-6199

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Fulminant liver failure in a child with invasive group A streptococcal infection

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