Scientific article
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Use of corticosteroids after hepatoportoenterostomy for bile drainage in infants with biliary atresia: the START randomized clinical trial

Published inJAMA, vol. 311, no. 17, p. 1750-1759
Publication date2014
Abstract

Biliary atresia is the most common cause of end-stage liver disease in children. Controversy exists as to whether use of steroids after hepatoportoenterostomy improves clinical outcome.

Keywords
  • Administration, Oral
  • Adrenal Cortex Hormones/administration & dosage/adverse effects
  • Biliary Atresia/drug therapy/surgery
  • Bilirubin/blood
  • Double-Blind Method
  • Drainage/methods
  • Female
  • Humans
  • Infant
  • Infusions, Intravenous
  • Male
  • Methylprednisolone/administration & dosage/adverse effects
  • Portoenterostomy, Hepatic
  • Prednisolone/administration & dosage/adverse effects
  • Survival Analysis
  • Treatment Outcome
Citation (ISO format)
BEZERRA, Jorge A et al. Use of corticosteroids after hepatoportoenterostomy for bile drainage in infants with biliary atresia: the START randomized clinical trial. In: JAMA, 2014, vol. 311, n° 17, p. 1750–1759. doi: 10.1001/jama.2014.2623
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Article (Published version)
accessLevelPublic
Identifiers
Journal ISSN0098-7484
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1065downloads

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