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Potential non-T cells source of interleukin-4 in food allergy

Contributors

Caubet, Jean-Christoph Roger J-P; Masilamani, Madhan; Rivers, Neisha A; Mayer, Lloyd; Sampson, Hugh A

Published in

Pediatric allergy and immunology, vol. 25, no. 3, p. 243-249

Publication date

2014

Abstract

Recently, a study from the Consortium of Food Allergy Research (CoFAR) showed that allergen-induced IL-4 expression in CD25(+) mononuclear cells was increased in allergic patients. However, they did not find the expected increase in GATA-3 expression, suggesting that allergen-induced IL-4 might not be of T-cell origin. We sought to determine whether other cell types were responsible for the increased IL-4 expression in the CD25(+) cell population.

Keywords

  • Adolescent
  • Adult
  • Antigen Presentation
  • Antigens, CD63/analysis
  • Basophils/immunology
  • Child
  • Child, Preschool
  • Female
  • Food Hypersensitivity/immunology
  • Humans
  • Infant
  • Interleukin-2 Receptor alpha Subunit/analysis
  • Interleukin-4/biosynthesis
  • Male

UNIGE affiliation entities

UNIGE research groups

Citation (ISO format)

CAUBET, Jean-Christoph Roger J-P et al. Potential non-T cells source of interleukin-4 in food allergy. In: Pediatric allergy and immunology, 2014, vol. 25, n° 3, p. 243–249. doi: 10.1111/pai.12207

Main files (1)

Article (Published version)

Identifiers

Journal ISSN

0905-6157
595views
498downloads

Technical informations

Creation

17/03/2015 10:43:00

First validation

17/03/2015 10:43:00

Update

14/03/2023 23:08:09

Status update

14/03/2023 23:08:08

Last indexation

30/10/2024 23:47:44
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