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Osteoarticular infections in young children: what has changed over the last years?

Kampouroglou, Georgios
Valaikaite, Raimonda
Anderson della Llana, Rebecca
Published in Swiss Medical Weekly. 2014, vol. 144, p. w13971
Abstract Osteoarticular infections remain a significant cause of morbidity worldwide in young children. They can have a devastating impact with a high rate of serious and long-lasting sequelae, especially on remaining growth. Depending on the localisation of infection, they manifest as osteomyelitis, septic arthritis, a combination of both (i.e., osteomyelitis with adjacent septic arthritis) or spondylodiscitis. Osteoarticular infections can be divided into three types according to the source of infection: haematogenous; secondary to contiguous infection; or secondary to direct inoculation. During the last few years, many principles regarding diagnostic assays and the microbiological causes of these infections have evolved in a significant manner. In the present current-opinion review, we discuss recent concepts regarding epidemiology, physiopathology, and the microbiology of bone and joint infections in young children, as well as clinical presentations, diagnosis, and treatment of these infections. Clinicians caring for children need to be especially well versed in these newer concepts as they can be used to guide evaluation and treatment.
Keywords Anti-Bacterial Agents/therapeutic useArthritis, Infectious/diagnosis/epidemiology/microbiology/therapyChild, PreschoolDiscitis/diagnosis/epidemiology/microbiology/therapyHumansInfantKingella kingae/isolation & purificationNeisseriaceae Infections/complications/microbiologyOsteomyelitis/diagnosis/epidemiology/microbiology/therapyRespiratory Tract Infections/complicationsStaphylococcal Infections/complications/microbiologyStaphylococcus aureusTuberculosis, Osteoarticular/epidemiology
PMID: 24921410
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Article (Published version) (703 Kb) - public document Free access
Research group Groupe Lascombes Pierre (orthopédie pédiatrique) (917)
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CERONI, Dimitri et al. Osteoarticular infections in young children: what has changed over the last years?. In: Swiss Medical Weekly, 2014, vol. 144, p. w13971. https://archive-ouverte.unige.ch/unige:55194

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Deposited on : 2015-04-07

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