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Impact of the lab-score on antibiotic prescription rate in children with fever without source: a randomized controlled trial

ContributorsLacroix, Laurence Elisabeth; Manzano, Sergio; Vandertuin, Lynda; Hugon, Florence Anne-Marie; Galetto-Lacour, Annick; Gervaix, Alain
Published inPloS one, vol. 9, no. 12, e115061
Publication date2014
Abstract

The Lab-score, based on the combined determination of procalcitonin, C-reactive protein and urinary dipstick results, has been shown accurate in detecting serious bacterial infections (SBI) in children with fever without source (FWS) on retrospective cohorts. We aimed to prospectively assess the utility of the Lab-score in safely decreasing antibiotic prescriptions in children with FWS and to determine its diagnostic characteristics compared to common SBI biomarkers.

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LACROIX, Laurence Elisabeth et al. Impact of the lab-score on antibiotic prescription rate in children with fever without source: a randomized controlled trial. In: PloS one, 2014, vol. 9, n° 12, p. e115061. doi: 10.1371/journal.pone.0115061
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accessLevelPublic CC BY
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ISSN of the journal1932-6203
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