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Anaphylaxie aux colorants bleus

Langner-Viviani, F
Chappuis, S
Published in Revue médicale suisse. 2014, vol. 10, no. 426, p. 876-80
Abstract In medicine, vital blue dyes are mainly used for the evaluation of sentinel lymph nodes in oncologic surgery. Perioperative anaphylaxis to blue dyes is a rare but significant complication. Allergic reactions to blue dyes are supposedly IgE-mediated and mainly caused by triarylmethanes (patent blue and isosulfane blue) and less frequently by methylene blue. These substances usually do not feature on the anesthesia record and should not be omitted from the list of suspects having caused the perioperative reaction, in the same manner as latex and chlorhexidine. The diagnosis of hypersensitivity to vital blue dyes can be established by skin test. We illustrate this topic with three clinical cases.
Keywords AdultAnaphylaxis/chemically induced/diagnosis/immunologyColoring Agents/adverse effects/diagnostic useDrug Hypersensitivity/diagnosis/etiology/immunologyFemaleHumansImmunoglobulin E/immunologyMethylene Blue/adverse effects/diagnostic useMiddle AgedRosaniline Dyes/adverse effects/diagnostic useSkin Tests/methods
PMID: 24834647
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Research group Pathogenèse et traitement des allergies alimentaires (191)
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LANGNER-VIVIANI, F et al. Anaphylaxie aux colorants bleus. In: Revue médicale suisse, 2014, vol. 10, n° 426, p. 876-80. https://archive-ouverte.unige.ch/unige:55113

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Deposited on : 2015-04-02

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