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Massive cerebral edema after I.V. cyclosporin overdose |
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Published in | Transplantation. 2000, vol. 70, no. 8, p. 1259-60 | |
Abstract | We describe a patient who accidentally received an infusion of cyclosporin at a rate of 30 mg/hr during 13 hr instead of the prescribed dose of 3 mg/hr and who concomitantly developed massive intracerebral edema with brainstem compression and death. A cyclosporin level as high as 1700 ng/ml could have been reached before the drug was withdrawn. To the best of our knowledge, this is the first case of fatal cyclosporin overdose reported in an adult patient. | |
Keywords | Brain Edema/chemically induced — Cyclosporine/administration & dosage/adverse effects/blood — Drug Overdose/etiology — Humans — Injections, Intravenous — Male — Middle Aged | |
Identifiers | PMID: 11063353 | |
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Research group | Devenir des patients ayant séjourné aux soins intensifs de chirurgie (283) | |
Citation (ISO format) | DE PERROT, Marc Eugène Antoine et al. Massive cerebral edema after I.V. cyclosporin overdose. In: Transplantation, 2000, vol. 70, n° 8, p. 1259-60. https://archive-ouverte.unige.ch/unige:55096 |