Article (Published version) (724 Kb) - 
Free access
Highlights
More informations
Scientific Article
unige:5 
 |
In vivo methods for the assessment of topical drug bioavailability |
|
| Authors | ||
| Published in | Pharmaceutical Research. 2008, vol. 25, no. 1, p. 87-103 | |
| Abstract | This paper reviews some current methods for the in vivo assessment of local cutaneous bioavailability in humans after topical drug application. After an introduction discussing the importance of local drug bioavailability assessment and the limitations of model-based predictions, the focus turns to the relevance of experimental studies. The available techniques are then reviewed in detail, with particular emphasis on the tape stripping and microdialysis methodologies. Other less developed techniques, including the skin biopsy, suction blister, follicle removal and confocal Raman spectroscopy techniques are also described. | |
| Identifiers | PMID: 17985216 | |
| Full text | ||
| Structures | ||
| Research group | Open Access - Licence nationale de Springer | |
| Citation (ISO format) | HERKENNE, Christophe et al. In vivo methods for the assessment of topical drug bioavailability. In: Pharmaceutical Research, 2008, vol. 25, n° 1, p. 87-103. https://archive-ouverte.unige.ch/unige:5 |
336 hits 
33 downloads 
Contact an author
Update