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Synthesis of 3-hydroxyoxindoles by Pd-catalysed intramolecular nucleophilic addition of aryl halides to α-ketoamides

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Jia, Yi-Xia
Published in Chemical Communications. 2010, vol. 46, no. 1, p. 130-132
Abstract Pd/PtBu3-catalysed intramolecular nucleophilic addition of aryl halides to α-ketoamides in the presence of nBuOH and base has been realized with high yields, providing a new, direct, and efficient synthetic strategy to obtain 3-hydroxyoxindoles.
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JIA, Yi-Xia, KATAYEV, Dmitry, KUNDIG, Ernst Peter. Synthesis of 3-hydroxyoxindoles by Pd-catalysed intramolecular nucleophilic addition of aryl halides to α-ketoamides. In: Chemical Communications, 2010, vol. 46, n° 1, p. 130-132. https://archive-ouverte.unige.ch/unige:4865

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Deposited on : 2010-01-25

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