Article (Published version) (375 Kb) - Limited access to UNIGE
Virologic testing in bronchiolitis: does it change management decisions and predict outcomes?
|Published in||European Journal of Pediatrics. 2014, vol. 173, no. 11, p. 1429-35|
|Abstract||The aim of this study was to evaluate the clinical, therapeutic, laboratory, and radiological differences between respiratory syncytial virus (RSV) and non-RSV bronchiolitis in order to assess if the prior knowledge of viral etiology changed management decisions and would be able to predict outcomes. Medical charts of children <1 year admitted to the emergency department with bronchiolitis during two RSV seasons (2010-2012) were reviewed. We analyzed 221 episodes of bronchiolitis. The percentage of exams performed (95 % confidence interval (CI) 0.74-2.52), abnormal laboratory and radiological findings (95 % CI 0.53-16.89) did not differ between groups. RSV bronchiolitis had a more severe clinical course. However, virologic testing for RSV had low specificity in identifying at-risk patients for hospitalization, longer hospital length of stay, and need of oxygen therapy and nasogastric tube (44, 40, 42, and 35 %, respectively), and while statistically significant, the positive likelihood ratios were only slightly greater than 1.|
|Research groups||Etiologie des pneumonies et marqueurs inflammatoires chez l'enfant fébrile (183)|
Facteurs influençants le développement pulmonaire: étude translationnelle chez l'animal et l'homme (182)
|STOLLAR, Fabiola et al. Virologic testing in bronchiolitis: does it change management decisions and predict outcomes?. In: European Journal of Pediatrics, 2014, vol. 173, n° 11, p. 1429-35. doi: 10.1007/s00431-014-2334-2 https://archive-ouverte.unige.ch/unige:48457|