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Scientific article
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Virologic testing in bronchiolitis: does it change management decisions and predict outcomes?

Published inEuropean journal of pediatrics, vol. 173, no. 11, p. 1429-1435
Publication date2014
Abstract

The aim of this study was to evaluate the clinical, therapeutic, laboratory, and radiological differences between respiratory syncytial virus (RSV) and non-RSV bronchiolitis in order to assess if the prior knowledge of viral etiology changed management decisions and would be able to predict outcomes. Medical charts of children <1 year admitted to the emergency department with bronchiolitis during two RSV seasons (2010-2012) were reviewed. We analyzed 221 episodes of bronchiolitis. The percentage of exams performed (95 % confidence interval (CI) 0.74-2.52), abnormal laboratory and radiological findings (95 % CI 0.53-16.89) did not differ between groups. RSV bronchiolitis had a more severe clinical course. However, virologic testing for RSV had low specificity in identifying at-risk patients for hospitalization, longer hospital length of stay, and need of oxygen therapy and nasogastric tube (44, 40, 42, and 35 %, respectively), and while statistically significant, the positive likelihood ratios were only slightly greater than 1.

Citation (ISO format)
STOLLAR, Fabiola et al. Virologic testing in bronchiolitis: does it change management decisions and predict outcomes? In: European journal of pediatrics, 2014, vol. 173, n° 11, p. 1429–1435. doi: 10.1007/s00431-014-2334-2
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ISSN of the journal0340-6199
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