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Title

Virologic testing in bronchiolitis: does it change management decisions and predict outcomes?

Authors
Alcoba, Gabriel
Published in European Journal of Pediatrics. 2014, vol. 173, no. 11, p. 1429-35
Abstract The aim of this study was to evaluate the clinical, therapeutic, laboratory, and radiological differences between respiratory syncytial virus (RSV) and non-RSV bronchiolitis in order to assess if the prior knowledge of viral etiology changed management decisions and would be able to predict outcomes. Medical charts of children <1 year admitted to the emergency department with bronchiolitis during two RSV seasons (2010-2012) were reviewed. We analyzed 221 episodes of bronchiolitis. The percentage of exams performed (95 % confidence interval (CI) 0.74-2.52), abnormal laboratory and radiological findings (95 % CI 0.53-16.89) did not differ between groups. RSV bronchiolitis had a more severe clinical course. However, virologic testing for RSV had low specificity in identifying at-risk patients for hospitalization, longer hospital length of stay, and need of oxygen therapy and nasogastric tube (44, 40, 42, and 35 %, respectively), and while statistically significant, the positive likelihood ratios were only slightly greater than 1.
Identifiers
PMID: 24858463
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Structures
Research groups Facteurs influençants le développement pulmonaire: étude translationnelle chez l'animal et l'homme (182)
Etiologie des pneumonies et marqueurs inflammatoires chez l'enfant fébrile (183)
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STOLLAR, Fabiola et al. Virologic testing in bronchiolitis: does it change management decisions and predict outcomes?. In: European Journal of Pediatrics, 2014, vol. 173, n° 11, p. 1429-35. https://archive-ouverte.unige.ch/unige:48457

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Deposited on : 2015-03-26

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