UNIGE document Scientific Article
previous document  unige:48443  next document
add to browser collection
Title

Epidural sufentanil during paediatric cardiac surgery: effects on metabolic response and postoperative outcome

Authors
Bichel, T
Schlegel, S
Published in Paediatric Anaesthesia. 2000, vol. 10, no. 6, p. 609-17
Abstract The metabolic and neuroendocrine effects of caudal epidural analgesia were studied during paediatric cardiac surgery. Combined epidural and general anaesthesia (EPI group; n=12) was compared with deep opioid anaesthesia (DOA group; n=12). During anaesthesia and surgery, haemodynamic stability was similar in the two groups. There was no significant difference between groups concerning the metabolic response to surgery but circulating catecholamines were significantly lower in the EPI group during and after surgery. Perioperative release of IL-6 was higher in the EPI group possibly reflecting a longer aortic clamp time. Incidence of postoperative life-threatening dysrhythmias was very low in the two groups. No significant reduction of postoperative mechanical ventilation, intensive care unit or hospital stays was reported with epidural analgesia. The incidence of postoperative infections was higher than expected in the two groups because of the poor properative clinical status of most of the children included in the study.
Keywords Analgesia, EpiduralAnalgesics, OpioidAnesthesia, GeneralBlood Glucose/analysisC-Reactive Protein/analysisCardiac Surgical ProceduresCatecholamines/bloodChild, PreschoolGrowth Hormone/bloodHeart Defects, Congenital/surgeryHemodynamicsHumansHydrocortisone/bloodInfantInterleukin-6/bloodLactates/bloodPostoperative ComplicationsStress, Physiological/blood/etiology/physiopathologySufentanil
Identifiers
PMID: 11119193
Full text
Article (Published version) (111 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Structures
Research group Chirurgie cardio-vasculaire (105)
Citation
(ISO format)
BICHEL, T et al. Epidural sufentanil during paediatric cardiac surgery: effects on metabolic response and postoperative outcome. In: Paediatric Anaesthesia, 2000, vol. 10, n° 6, p. 609-17. https://archive-ouverte.unige.ch/unige:48443

178 hits

1 download

Update

Deposited on : 2015-03-25

Export document
Format :
Citation style :