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Title

Combined radioimmunotherapy and radiotherapy of liver metastases from colorectal cancer: a feasibility study

Authors
Mirimanoff, R
Pelegrin, A
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Published in Anticancer Research. 2000, vol. 20, no. 3B, p. 1889-96
Abstract A combination of radioimmunotherapy (RIT) and radiotherapy (RT) should allow one to increase the dose of radiation targeting a particular tumour without the concomitant increase of toxic side effects. This might be obtained if the dose limiting side effect of each individual radiation therapy concerned different organs.
Keywords AdultAnimalsAntibodies, Monoclonal/adverse effects/pharmacokinetics/therapeutic useBone Marrow Diseases/etiologyCarcinoembryonic Antigen/immunologyColorectal Neoplasms/pathologyCombined Modality TherapyDose FractionationDrug Administration ScheduleFeasibility StudiesFemaleHumansImmunoglobulin Fab Fragments/adverse effects/therapeutic useIodine Radioisotopes/adverse effects/pharmacokinetics/therapeutic useLiver Diseases/etiologyLiver Function TestsLiver Neoplasms/radiotherapy/secondary/therapyMaleMiceMice, NudeMiddle AgedPremedicationRadioimmunotherapy/adverse effectsRadiotherapy DosageRadiotherapy, High-Energy/adverse effectsTissue DistributionTreatment Outcome
Identifiers
PMID: 10928122
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Research group Groupe Roth Arnaud (oncologie) (285)
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BUCHEGGER, Franz et al. Combined radioimmunotherapy and radiotherapy of liver metastases from colorectal cancer: a feasibility study. In: Anticancer Research, 2000, vol. 20, n° 3B, p. 1889-96. https://archive-ouverte.unige.ch/unige:48439

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Deposited on : 2015-03-25

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