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Combined radioimmunotherapy and radiotherapy of liver metastases from colorectal cancer: a feasibility study |
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Published in | Anticancer research. 2000, vol. 20, no. 3B, p. 1889-96 | |
Abstract | A combination of radioimmunotherapy (RIT) and radiotherapy (RT) should allow one to increase the dose of radiation targeting a particular tumour without the concomitant increase of toxic side effects. This might be obtained if the dose limiting side effect of each individual radiation therapy concerned different organs. | |
Keywords | Adult — Animals — Antibodies, Monoclonal/adverse effects/pharmacokinetics/therapeutic use — Bone Marrow Diseases/etiology — Carcinoembryonic Antigen/immunology — Colorectal Neoplasms/pathology — Combined Modality Therapy — Dose Fractionation — Drug Administration Schedule — Feasibility Studies — Female — Humans — Immunoglobulin Fab Fragments/adverse effects/therapeutic use — Iodine Radioisotopes/adverse effects/pharmacokinetics/therapeutic use — Liver Diseases/etiology — Liver Function Tests — Liver Neoplasms/radiotherapy/secondary/therapy — Male — Mice — Mice, Nude — Middle Aged — Premedication — Radioimmunotherapy/adverse effects — Radiotherapy Dosage — Radiotherapy, High-Energy/adverse effects — Tissue Distribution — Treatment Outcome | |
Identifiers | PMID: 10928122 | |
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Research group | Groupe Roth Arnaud (oncologie) (285) | |
Citation (ISO format) | BUCHEGGER, Franz et al. Combined radioimmunotherapy and radiotherapy of liver metastases from colorectal cancer: a feasibility study. In: Anticancer research, 2000, vol. 20, n° 3B, p. 1889-96. https://archive-ouverte.unige.ch/unige:48439 |