Infections récurrentes des voies respiratoires inférieures de l&#039;enfant : quand et comment les investiguer ?

Posfay Barbe, Klara; Barazzone, Constance; Siegrist, Claire-Anne

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Title		Infections récurrentes des voies respiratoires inférieures de l'enfant : quand et comment les investiguer ?
Authors		Posfay Barbe, Klara Barazzone, Constance Siegrist, Claire-Anne
Published in		Revue médicale suisse. 2005, vol. 1, no. 7, p. 493-8
Abstract		Children with recurrent lower respiratory tract infections are often a challenge for their physicians. This article reviews the differential diagnosis of recurrent cough, bronchopneumonia and/or pneumonia in children and emphasizes on the necessity of preventing long-term complications of these infections. It also suggests a step-wise immunological work-up, which includes investigating a possible immune maturation delay or deficiency which could explain these symptoms. This work-up focuses on measuring antibody responses to pneumococci, followed by immunization when necessary, to rule out B cell dysfunction. Finally, this article also describes an upcoming study in Switzerland which will evaluate in 2005 the clinical and immunological outcome of these young patients.
Keywords		Antibodies, Bacterial/analysis — Child — Cough/complications — Humans — Recurrence — Respiratory Tract Infections/complications/etiology/immunology
Identifiers		PMID: 15790017
Full text		Article (Published version) (1.6 MB) - Limited access to UNIGE
Structures		Faculté de médecine / Section de médecine fondamentale / Département de pathologie et immunologie Faculté de médecine / Section de médecine clinique / Département de pédiatrie, gynécologie et obstétrique
Research groups		Centre de Vaccinologie et d'Immunologie néonatale (177) Facteurs influençants le développement pulmonaire: étude translationnelle chez l'animal et l'homme (182) Recherche en infectiologie pédiatrique et en pédiatrie générale (853)
Citation (ISO format)		POSFAY BARBE, Klara, BARAZZONE, Constance, SIEGRIST, Claire-Anne. Infections récurrentes des voies respiratoires inférieures de l'enfant : quand et comment les investiguer ?. In: Revue médicale suisse, 2005, vol. 1, n° 7, p. 493-8. https://archive-ouverte.unige.ch/unige:48436