Influence of IFNL3/4 Polymorphisms on the Incidence of Cytomegalovirus Infection After Solid-Organ Transplantation

Manuel, Oriol; Wójtowicz, Agnieszka; Bibert, Stéphanie; Mueller, Nicolas J.; Van Delden, Christian; Hirsch, Hans H.; Steiger, Juerg; Stern, Martin; Egli, Adrian; Garzoni, Christian; Binet, Isabelle; Weisser, Maja; Berger, Christoph; Cusini, Alexia; Meylan, Pascal; Pascual, Manuel Antonio; Bochud, Pierre-Yves

doi:10.1093/infdis/jiu557

Scientific article

English

Influence of IFNL3/4 Polymorphisms on the Incidence of Cytomegalovirus Infection After Solid-Organ Transplantation

ContributorsManuel, Oriol; Wójtowicz, Agnieszka; Bibert, Stéphanie; Mueller, Nicolas J.; Van Delden, Christian; Hirsch, Hans H.; Steiger, Juerg; Stern, Martin; Egli, Adrian; Garzoni, Christian; Binet, Isabelle; Weisser, Maja; Berger, Christoph; Cusini, Alexia; Meylan, Pascal; Pascual, Manuel Antonio; Bochud, Pierre-Yves

Published inThe Journal of infectious diseases, vol. 211, no. 6, p. 906-914

Publication date2015

Abstract

Polymorphisms in IFNL3 and IFNL4, the genes encoding interferon λ3 and interferon λ4, respectively, have been associated with reduced hepatitis C virus clearance. We explored the role of such polymorphisms on the incidence of cytomegalovirus (CMV) infection in solid-organ transplant recipients.

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Citation (ISO format)

MANUEL, Oriol et al. Influence of IFNL3/4 Polymorphisms on the Incidence of Cytomegalovirus Infection After Solid-Organ Transplantation. In: The Journal of infectious diseases, 2015, vol. 211, n° 6, p. 906–914. doi: 10.1093/infdis/jiu557

Article (Published version)

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PID : unige:48093
DOI : 10.1093/infdis/jiu557
PMID : 25301956

Journal ISSN0022-1899

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Influence of IFNL3/4 Polymorphisms on the Incidence of Cytomegalovirus Infection After Solid-Organ Transplantation

Polymorphisms in IFNL3 and IFNL4, the genes encoding interferon λ3 and interferon λ4, respectively, have been associated with reduced hepatitis C virus clearance. We explored the role of such polymorphisms on the incidence of cytomegalovirus (CMV) infection in solid-organ transplant recipients.

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