Microencapsulated human mesenchymal stem cells decrease liver fibrosis in mice

Meier, Raphaël; Mahou, Redouan; Morel, Philippe; Meyer, Jérémy; Montanari, Elisa; Muller, Yannick; Christofilopoulos, Panayiotis; Wandrey, Christine; Gonelle-Gispert, Carmen; Buehler, Leo Hans

doi:10.1016/j.jhep.2014.10.030

Scientific article

Open access

English

Microencapsulated human mesenchymal stem cells decrease liver fibrosis in mice

ContributorsMeier, Raphaël; Mahou, Redouan; Morel, Philippe; Meyer, Jérémy

; Montanari, Elisa; Muller, Yannick; Christofilopoulos, Panayiotis; Wandrey, Christine; Gonelle-Gispert, Carmen; Buehler, Leo Hans

Published inJournal of hepatology, vol. 62, no. 3, p. 634-641

Publication date2015

Abstract

Mesenchymal stem cell (MSC) transplantation was shown to be effective for the treatment of liver fibrosis, but the mechanisms of action are not yet fully understood. We transplanted encapsulated human MSCs in two mouse models of liver fibrosis to determine the mechanisms behind the protective effect.

Affiliation

Faculté de médecine / Section de médecine clinique / Département de chirurgie

Research group

Citation (ISO format)

MEIER, Raphaël et al. Microencapsulated human mesenchymal stem cells decrease liver fibrosis in mice. In: Journal of hepatology, 2015, vol. 62, n° 3, p. 634–641. doi: 10.1016/j.jhep.2014.10.030

Article (Published version)

Identifiers

PID : unige:48092
DOI : 10.1016/j.jhep.2014.10.030
PMID : 25450712

ISSN of the journal0168-8278

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Microencapsulated human mesenchymal stem cells decrease liver fibrosis in mice

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