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Title

Early assessment of apoptosis in isolated islets of Langerhans

Authors
Cattan, P
Schena, S
Molano, R D
Pileggi, A
Vizzardelli, C
Ricordi, C
Inverardi, L
Published in Transplantation. 2001, vol. 71, no. 7, p. 857-62
Abstract There is substantial evidence to link early graft loss after islet transplantation to isolation-induced islet cell apoptosis. Measurement of caspase 3 activity and detection of the lost cell membrane asymmetry, revealed by annexin V binding, are newly available assays that allow the analysis of early events of apoptosis.
Keywords AnimalsAnnexin A5/metabolismApoptosisBiological MarkersCaspase 3Caspases/metabolismDNA FragmentationElectrophoresis, Polyacrylamide GelIn Situ Nick-End LabelingIn Vitro TechniquesIslets of Langerhans/cytology/metabolism/physiologyRatsRats, Inbred Lew
Identifiers
PMID: 11349716
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Article (Author postprint) (1.1 MB) - document accessible for UNIGE members only Limited access to UNIGE
Structures
Research group La transplantation d'îlots de Langerhans (623)
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CATTAN, P et al. Early assessment of apoptosis in isolated islets of Langerhans. In: Transplantation, 2001, vol. 71, n° 7, p. 857-62. https://archive-ouverte.unige.ch/unige:47546

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Deposited on : 2015-03-04

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