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Fibrillary structure is key for hemostasis: a similar effect of collagen fleece and oxidized cellulose on experimental hemorrhagic brain injury

ContributorsTessitore, Enrico; Schatlo, Bawarjan; Schaller, Karl Lothard; Schonauer, Claudio
Published inJournal of neurological surgery. Part A, Central European neurosurgery, vol. 73, no. 2, p. 89-92
Publication date2012
Abstract

The choice of the ideal hemostatic agent for intraoperative cerebral bleeding is under continuous debate. Our aim was to assess the influence of such materials on bleeding time in hemorrhagic cerebral contusions. We compared oxidized regenerated cellulose in fibrillar form (ORC) to microfibrillar collagen fleece (CF) in an experimental study.

Keywords
  • Animals
  • Bleeding Time
  • Brain Hemorrhage, Traumatic/drug therapy/pathology/physiopathology
  • Brain Injuries/complications/physiopathology
  • Cellulose, Oxidized/chemistry/pharmacology
  • Coagulants/chemistry/pharmacology
  • Collagen/chemistry/pharmacology
  • Disease Models, Animal
  • Hemostatic Techniques/trends
  • Male
  • Rats
  • Rats, Sprague-Dawley
  • Treatment Outcome
Affiliation
Research group
Citation (ISO format)
TESSITORE, Enrico et al. Fibrillary structure is key for hemostasis: a similar effect of collagen fleece and oxidized cellulose on experimental hemorrhagic brain injury. In: Journal of neurological surgery. Part A, Central European neurosurgery, 2012, vol. 73, n° 2, p. 89–92. doi: 10.1055/s-0032-1309064
Identifiers
ISSN of the journal2193-6315
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