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Scientific article
English

Comparison of microsatellite instability and chromosomal instability in predicting survival of patients with T3N0 colorectal cancer

ContributorsGervaz, Pascal; Cerottini, Jean-Philippe; Bouzourene, Hanifa; Hahnloser, Dieter; Doan, Christy L; Benhattar, Jean; Chaubert, Pascal; Secic, Michelle; Gillet, Michel; Carethers, John M
Published inSurgery, vol. 131, no. 2, p. 190-197
Publication date2002
Abstract

At least 2 apparently independent mechanisms, microsatellite instability (MSI) and chromosomal instability, are implicated in colorectal tumorigenesis. Their respective roles in predicting clinical outcomes of patients with T3N0 colorectal cancer remain unknown.

Keywords
  • Adult
  • Aged
  • Chromosome Aberrations
  • Colorectal Neoplasms/genetics/mortality
  • Female
  • Genes, ras
  • Humans
  • Male
  • Microsatellite Repeats
  • Middle Aged
  • Mutation
  • Survival Rate
  • Tumor Suppressor Protein p53/analysis
Affiliation entities
Research groups
Citation (ISO format)
GERVAZ, Pascal et al. Comparison of microsatellite instability and chromosomal instability in predicting survival of patients with T3N0 colorectal cancer. In: Surgery, 2002, vol. 131, n° 2, p. 190–197. doi: 10.1067/msy.2002.119816
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
Journal ISSN0039-6060
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Creation29/01/2015 14:48:00
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Update14/03/2023 22:47:33
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