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Scientific article
English

Comparison of microsatellite instability and chromosomal instability in predicting survival of patients with T3N0 colorectal cancer

ContributorsGervaz, Pascal; Cerottini, Jean-Philippe; Bouzourene, Hanifa; Hahnloser, Dieter; Doan, Christy L; Benhattar, Jean; Chaubert, Pascal; Secic, Michelle; Gillet, Michel; Carethers, John M
Published inSurgery, vol. 131, no. 2, p. 190-197
Publication date2002
Abstract

At least 2 apparently independent mechanisms, microsatellite instability (MSI) and chromosomal instability, are implicated in colorectal tumorigenesis. Their respective roles in predicting clinical outcomes of patients with T3N0 colorectal cancer remain unknown.

Keywords
  • Adult
  • Aged
  • Chromosome Aberrations
  • Colorectal Neoplasms/genetics/mortality
  • Female
  • Genes, ras
  • Humans
  • Male
  • Microsatellite Repeats
  • Middle Aged
  • Mutation
  • Survival Rate
  • Tumor Suppressor Protein p53/analysis
UNIGE affiliation entities
UNIGE research groups
Citation (ISO format)
GERVAZ, Pascal et al. Comparison of microsatellite instability and chromosomal instability in predicting survival of patients with T3N0 colorectal cancer. In: Surgery, 2002, vol. 131, n° 2, p. 190–197. doi: 10.1067/msy.2002.119816
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
Journal ISSN0039-6060
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Update14/03/2023 22:47:33
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