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Title

Tocilizumab monotherapy versus adalimumab monotherapy for treatment of rheumatoid arthritis (ADACTA): a randomised, double-blind, controlled phase 4 trial
Authors
Gabay, Cem
Emery, Paul
van Vollenhoven, Ronald
Dikranian, Ara
Alten, Rieke
Pavelka, Karel
Klearman, Micki
Musselman, David
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Published in The Lancet. 2013, vol. 381, no. 9877, p. 1541-50
Abstract Roughly a third of patients with rheumatoid arthritis treated with biological treatments receive them as monotherapy. Tocilizumab--an inhibitor of interleukin 6 receptor signalling--has been studied as monotherapy in several clinical trials. We assessed the efficacy and safety of tocilizumab monotherapy compared with adalimumab monotherapy for patients with rheumatoid arthritis.
Keywords Adult — Aged — Antibodies, Monoclonal, Humanized/therapeutic use — Antirheumatic Agents/therapeutic use — Arthritis, Rheumatoid/therapy — Double-Blind Method — Female — Humans — Male — Middle Aged
Identifiers
PMID: 23515142
Full text
Article (Published version) (413 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Structures
Faculté de médecine / Section de médecine clinique / Département de médecine interne des spécialités
Research group Mécanisme de l'inflammation articulaire (44)
Citation
(ISO format) 		GABAY, Cem et al. Tocilizumab monotherapy versus adalimumab monotherapy for treatment of rheumatoid arthritis (ADACTA): a randomised, double-blind, controlled phase 4 trial. In: The Lancet, 2013, vol. 381, n° 9877, p. 1541-50. https://archive-ouverte.unige.ch/unige:46003

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Deposited on : 2015-01-29

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