Inflammation: IL-36 has proinflammatory effects in skin but not in joints

Dietrich, Damien; Gabay, Cem

doi:10.1038/nrrheum.2014.156

Scientific article

English

Inflammation: IL-36 has proinflammatory effects in skin but not in joints

ContributorsDietrich, Damien; Gabay, Cem

Published inNature reviews. Rheumatology, vol. 10, no. 11, p. 639-640

Publication date2014

Abstract

Given the known involvement of IL-36 in psoriasis it might be surprising that the latest mouse models show that inhibiting IL-36 signalling does not alter the course of inflammatory arthritis. Can we now add IL-36 to the list of inflammatory mediators that are not viable DMARD targets?

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Inflammation articulaire (44)

Citation (ISO format)

DIETRICH, Damien, GABAY, Cem. Inflammation: IL-36 has proinflammatory effects in skin but not in joints. In: Nature reviews. Rheumatology, 2014, vol. 10, n° 11, p. 639–640. doi: 10.1038/nrrheum.2014.156

Article (Published version)

Identifiers

PID : unige:45955
DOI : 10.1038/nrrheum.2014.156
PMID : 25201385

Journal ISSN1759-4790

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Inflammation: IL-36 has proinflammatory effects in skin but not in joints

Given the known involvement of IL-36 in psoriasis it might be surprising that the latest mouse models show that inhibiting IL-36 signalling does not alter the course of inflammatory arthritis. Can we now add IL-36 to the list of inflammatory mediators that are not viable DMARD targets?

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