UNIGE document Scientific Article
previous document  unige:45809  next document
add to browser collection
Title

Consensus statement on blocking the effects of interleukin-6 and in particular by interleukin-6 receptor inhibition in rheumatoid arthritis and other inflammatory conditions

Authors
Smolen, Josef S
Schoels, Monika M
Nishimoto, Norihiro
Breedveld, Ferdinand C
Burmester, Gerd R
Dougados, Maxime
Emery, Paul
Ferraccioli, Gianfranco
show hidden authors show all authors [1 - 35]
Published in Annals of the Rheumatic Diseases. 2013, vol. 72, no. 4, p. 482-92
Abstract Since approval of tocilizumab (TCZ) for treatment of rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA), interleukin 6 (IL-6) pathway inhibition was evaluated in trials of TCZ and other agents targeting the IL-6 receptor and ligand in various RA populations and other inflammatory diseases. This consensus document informs on interference with the IL-6 pathway based on evidence and expert opinion.
Keywords Antibodies, Monoclonal, Humanized/administration & dosage/adverse effectsAntirheumatic Agents/administration & dosage/adverse effectsArthritis, Rheumatoid/drug therapy/immunologyDrug Monitoring/methodsHumansInflammation/drug therapy/immunologyInterleukin-6/antagonists & inhibitorsReceptors, Interleukin-6/antagonists & inhibitors
Identifiers
PMID: 23172750
Full text
Article (Published version) (238 Kb) - public document Free access
Structures
Research group Mécanisme de l'inflammation articulaire (44)
Citation
(ISO format)
SMOLEN, Josef S et al. Consensus statement on blocking the effects of interleukin-6 and in particular by interleukin-6 receptor inhibition in rheumatoid arthritis and other inflammatory conditions. In: Annals of the Rheumatic Diseases, 2013, vol. 72, n° 4, p. 482-92. https://archive-ouverte.unige.ch/unige:45809

178 hits

118 downloads

Update

Deposited on : 2015-01-23

Export document
Format :
Citation style :