Phase II study of capecitabine and oxaliplatin in first- and second-line treatment of advanced or metastatic colorectal cancer

Borner, Markus M; Dietrich, Daniel; Stupp, Roger; Morant, Rudolf; Honegger, Hanspeter; Wernli, Martin; Herrmann, Richard; Pestalozzi, Bernhard C; Saletti, Piercarlo; Hanselmann, Silvia; Müller, Samuel; Brauchli, Peter; Castiglione-Gertsch, Monica; Goldhirsch, Aron; Roth, Arnaud

doi:10.1200/JCO.2002.07.087

Scientific article

English

Phase II study of capecitabine and oxaliplatin in first- and second-line treatment of advanced or metastatic colorectal cancer

ContributorsBorner, Markus M; Dietrich, Daniel; Stupp, Roger; Morant, Rudolf; Honegger, Hanspeter; Wernli, Martin; Herrmann, Richard; Pestalozzi, Bernhard C; Saletti, Piercarlo; Hanselmann, Silvia; Müller, Samuel; Brauchli, Peter; Castiglione-Gertsch, Monica; Goldhirsch, Aron; Roth, Arnaud

Published inJournal of clinical oncology, vol. 20, no. 7, p. 1759-1766

Publication date2002

Abstract

To determine the efficacy and tolerability of combining oxaliplatin with capecitabine in the treatment of advanced nonpretreated and pretreated colorectal cancer.

Keywords

Adenocarcinoma/drug therapy
Adult
Aged
Antimetabolites, Antineoplastic/administration & dosage
Antineoplastic Combined Chemotherapy Protocols/adverse effects/therapeutic use
Colorectal Neoplasms/drug therapy
Deoxycytidine/administration & dosage/analogs & derivatives
Diarrhea/chemically induced
Drug Administration Schedule
Female
Fluorouracil/analogs & derivatives
Humans
Male
Middle Aged
Neoplasm Staging
Organoplatinum Compounds/administration & dosage
Treatment Outcome

Affiliation entities

Research groups

Groupe Roth Arnaud (oncologie) (285)

Citation (ISO format)

BORNER, Markus M et al. Phase II study of capecitabine and oxaliplatin in first- and second-line treatment of advanced or metastatic colorectal cancer. In: Journal of clinical oncology, 2002, vol. 20, n° 7, p. 1759–1766. doi: 10.1200/JCO.2002.07.087

Article (Published version)

Identifiers

PID : unige:45717
DOI : 10.1200/JCO.2002.07.087
PMID : 11919232

Journal ISSN0732-183X

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Phase II study of capecitabine and oxaliplatin in first- and second-line treatment of advanced or metastatic colorectal cancer

To determine the efficacy and tolerability of combining oxaliplatin with capecitabine in the treatment of advanced nonpretreated and pretreated colorectal cancer.

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