Cryopreservation and mycophenolate therapy are detrimental to hematopoietic progenitor cells

Buehler, Leo Hans; Kurilla-Mahon, Barbara; Chang, Qing; Abraham, Sonny; Alwayn, Ian P J; Appel, James Z (3rd); Newman, Dawne; Awwad, Michel; White-Scharf, Mary E; Sackstein, Roberto; Sachs, David H; Cooper, David K C; Down, Julian D

doi:10.1097/01.TP.0000031947.81048.DA

Scientific article

English

Cryopreservation and mycophenolate therapy are detrimental to hematopoietic progenitor cells

ContributorsBuehler, Leo Hans; Kurilla-Mahon, Barbara; Chang, Qing; Abraham, Sonny; Alwayn, Ian P J; Appel, James Z (3rd); Newman, Dawne; Awwad, Michel; White-Scharf, Mary E; Sackstein, Roberto; Sachs, David H; Cooper, David K C; Down, Julian D

Published inTransplantation, vol. 74, no. 8, p. 1159-1166

Publication date2002

Abstract

The aim of the present study was to determine whether certain components of nonmyeloablative regimens for hematopoietic cell transplantation might compromise the growth of hematopoietic progenitors.

Keywords

Animals
Cell Division/drug effects
Cell Survival/drug effects
Cryopreservation
Female
Hematopoietic Stem Cell Transplantation
Hematopoietic Stem Cells/cytology/drug effects
Humans
Immunosuppressive Agents/blood/pharmacology
In Vitro Techniques
Leukapheresis
Male
Mycophenolic Acid/analogs & derivatives/blood/pharmacology
Papio
Swine, Miniature
Transplantation, Heterologous

Affiliation

Faculté de médecine / Section de médecine clinique / Département de chirurgie

Research group

Cultures cellulaires et transplantations (519)

Citation (ISO format)

BUEHLER, Leo Hans et al. Cryopreservation and mycophenolate therapy are detrimental to hematopoietic progenitor cells. In: Transplantation, 2002, vol. 74, n° 8, p. 1159–1166. doi: 10.1097/01.TP.0000031947.81048.DA

Article (Published version)

Identifiers

PID : unige:45713
DOI : 10.1097/01.TP.0000031947.81048.DA
PMID : 12438964

ISSN of the journal0041-1337

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Cryopreservation and mycophenolate therapy are detrimental to hematopoietic progenitor cells

The aim of the present study was to determine whether certain components of nonmyeloablative regimens for hematopoietic cell transplantation might compromise the growth of hematopoietic progenitors.

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