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Autoanticorps en neurologie : implications cliniques

Published in Revue médicale suisse. 2009, vol. 5, no. 201, p. 942-950
Abstract Autoantibodies are defined as antibodies directed against self antigens, i.e., against a normal antigenic endogenous tissue constituent. They can be the immediate cause of the neurological syndrome or be detected as an epiphenomenon of the pathogenic process. Autoantibodies are often considered useful biomarkers for the improvement of diagnostic accuracy, for the staging of disease progression or for the follow up of a biological response to a therapeutic intervention. The purpose of this article is to review the autoantibodies that are available to investigate immune-mediated neurological conditions. The detection of some of these autoantibodies may help the clinician to establish a definite diagnosis which may further facilitate the therapeutic decision.
Keywords Autoantibodies/analysisAutoimmune Diseases of the Nervous System/immunologyBiological Markers/analysisHumans
PMID: 19476056
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Other version: http://rms.medhyg.ch/numero-201-page-942.htm
Research groups Groupe Pierre Burkhard (neurologie) (154)
Scléroses en plaques, neuroimmunologie, encéphalite autoimmune expérimentale (843)
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LALIVE D'EPINAY, Patrice et al. Autoanticorps en neurologie : implications cliniques. In: Revue médicale suisse, 2009, vol. 5, n° 201, p. 942-950. https://archive-ouverte.unige.ch/unige:45473

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Deposited on : 2015-01-19

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