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Adrenal cortical phaeochromocytoma: a case report of a rare entity

Simon, S
Meier, C
Published in Experimental and Clinical Endocrinology and Diabetes. 2003, vol. 111, no. 2, p. 111-4
Abstract Adrenal cortical phaeochromocytomas (pseudo-phaeochromocytomas) are a very rare entity and a diagnostic challenge. Of the few cases previously reported, most have incomplete data or lack clinical and biochemical follow-up documenting the cure of the excess secretion of catecholamines after resection of the tumour. We report herein a 62-year-old patient with clinical and biochemical findings diagnostic of a phaeochromocytoma associated with a 2-cm adrenal mass on CT scan. Surgery revealed the presence of an adrenal cortical adenoma with positive staining for the neuroendocrine marker synaptophysin, but negative for chromogranin, as has been previously reported for these rare cortical phaeochromocytomas. After removal of the tumour the clinical symptoms resolved and biochemical markers normalized, demonstrating the causal relationship between the cortical tumour and the excess production of catecholamines.
Keywords Adrenal Cortex Neoplasms/pathology/radiography/surgery/urineAdrenalectomy/methodsBiological Markers/urineHumansLaparoscopyMaleMetanephrine/urineMiddle AgedPheochromocytoma/pathology/radiography/surgery/urineTomography, X-Ray ComputedTreatment Outcome
PMID: 12746763
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Research group Groupe Iselin Christophe (urologie) (106)
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SIMON, S et al. Adrenal cortical phaeochromocytoma: a case report of a rare entity. In: Experimental and Clinical Endocrinology and Diabetes, 2003, vol. 111, n° 2, p. 111-4. https://archive-ouverte.unige.ch/unige:45362

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Deposited on : 2015-01-15

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