UNIGE document Scientific Article - Letter
previous document  unige:45251  next document
add to browser collection
Title

Molecular analyses of the LRRK2 gene in European and North African autosomal dominant Parkinson's disease

Authors
Lesage, S
Condroyer, C
Lannuzel, A
Lohmann, E
Troiano, A
Tison, F
Damier, P
Thobois, S
show hidden authors show all authors [1 - 17]
CollaborationWith : Pollak, Pierre
Published in Journal of Medical Genetics. 2009, vol. 46, no. 7, p. 458-64
Abstract Mutations in the leucine-rich-repeat kinase 2 (LRRK2) gene have been identified in families with autosomal dominant Parkinson's disease (ADPD), the most common of which is the p.G2019S substitution that has been found at varying frequencies worldwide. Because of the size of the LRRK2 gene, few studies have analysed the entire gene in large series of ADPD families.
Keywords AdolescentAdultAfrican Continental Ancestry Group/geneticsAgedAged, 80 and overAnalysis of VarianceChi-Square DistributionDNA Mutational Analysis/methodsEuropean Continental Ancestry Group/geneticsFemaleGene FrequencyHumansMaleMiddle AgedMutationParkinsonian Disorders/diagnosis/geneticsPedigreeProtein-Serine-Threonine Kinases/genetics
Identifiers
PMID: 19357115
Full text
Article (Published version) (387 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Structures
Research group Maladie de Parkinson (911)
Citation
(ISO format)
LESAGE, S et al. Molecular analyses of the LRRK2 gene in European and North African autosomal dominant Parkinson's disease. In: Journal of Medical Genetics, 2009, vol. 46, n° 7, p. 458-64. https://archive-ouverte.unige.ch/unige:45251

147 hits

0 download

Update

Deposited on : 2015-01-14

Export document
Format :
Citation style :