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Title

Timing of antiepileptic drug withdrawal and long-term seizure outcome after paediatric epilepsy surgery (TimeToStop): a retrospective observational study

Authors
Boshuisen, Kim
Arzimanoglou, Alexis
Cross, J Helen
Uiterwaal, Cuno S P M
Polster, Tilman
van Nieuwenhuizen, Onno
Braun, Kees P J
CollaborationWith : Seeck, Margitta
Published in The Lancet Neurology. 2012, vol. 11, no. 9, p. 784-91
Abstract Postoperative antiepileptic drug (AED) withdrawal practices remain debatable and little is known about the optimum timing. We hypothesised that early AED withdrawal does not affect long-term seizure outcome but allows identification of incomplete surgical success earlier than late withdrawal. We aimed to assess the relation between timing of AED withdrawal and subsequent seizure recurrence and long-term seizure outcome.
Keywords Anticonvulsants/therapeutic useChildChild, PreschoolElectroencephalographyEpilepsy/diagnosis/drug therapy/surgeryEurope/epidemiologyFemaleHemispherectomy/methodsHumansInfantLongitudinal StudiesMagnetic Resonance ImagingMaleProportional Hazards ModelsRetrospective StudiesTime Factors
Identifiers
PMID: 22841352
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Article (Published version) (141 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Structures
Research group Epilepsie et Chirurgie (149)
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BOSHUISEN, Kim et al. Timing of antiepileptic drug withdrawal and long-term seizure outcome after paediatric epilepsy surgery (TimeToStop): a retrospective observational study. In: The Lancet Neurology, 2012, vol. 11, n° 9, p. 784-91. https://archive-ouverte.unige.ch/unige:45234

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Deposited on : 2015-01-14

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