en
Scientific article
English

Timing of antiepileptic drug withdrawal and long-term seizure outcome after paediatric epilepsy surgery (TimeToStop): a retrospective observational study

CollaboratorsSeeck, Margitta
Published inLancet neurology, vol. 11, no. 9, p. 784-791
Publication date2012
Abstract

Postoperative antiepileptic drug (AED) withdrawal practices remain debatable and little is known about the optimum timing. We hypothesised that early AED withdrawal does not affect long-term seizure outcome but allows identification of incomplete surgical success earlier than late withdrawal. We aimed to assess the relation between timing of AED withdrawal and subsequent seizure recurrence and long-term seizure outcome.

Keywords
  • Anticonvulsants/therapeutic use
  • Child
  • Child, Preschool
  • Electroencephalography
  • Epilepsy/diagnosis/drug therapy/surgery
  • Europe/epidemiology
  • Female
  • Hemispherectomy/methods
  • Humans
  • Infant
  • Longitudinal Studies
  • Magnetic Resonance Imaging
  • Male
  • Proportional Hazards Models
  • Retrospective Studies
  • Time Factors
Citation (ISO format)
BOSHUISEN, Kim et al. Timing of antiepileptic drug withdrawal and long-term seizure outcome after paediatric epilepsy surgery (TimeToStop): a retrospective observational study. In: Lancet neurology, 2012, vol. 11, n° 9, p. 784–791. doi: 10.1016/S1474-4422(12)70165-5
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Article (Published version)
accessLevelRestricted
Identifiers
ISSN of the journal1474-4422
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