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Scientific article
Open access
English

Large-scale replication and heterogeneity in Parkinson disease genetic loci

ContributorsSharma, Manu; GEO-PD Consortium
CollaboratorsPollak, Pierre
Published inNeurology, vol. 79, no. 7, p. 659-667
Publication date2012
Abstract

Eleven genetic loci have reached genome-wide significance in a recent meta-analysis of genome-wide association studies in Parkinson disease (PD) based on populations of Caucasian descent. The extent to which these genetic effects are consistent across different populations is unknown.

Keywords
  • Aged
  • Alleles
  • Case-Control Studies
  • Female
  • Gene Frequency
  • Genetic Loci
  • Genetic Predisposition to Disease
  • Genome-Wide Association Study
  • Genotype
  • Humans
  • Male
  • Middle Aged
  • Parkinson Disease/genetics
  • Polymorphism, Single Nucleotide
Citation (ISO format)
SHARMA, Manu. Large-scale replication and heterogeneity in Parkinson disease genetic loci. In: Neurology, 2012, vol. 79, n° 7, p. 659–667. doi: 10.1212/WNL.0b013e318264e353
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Article (Published version)
accessLevelPublic
Identifiers
ISSN of the journal0028-3878
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