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Squamous cell carcinoma of the anus: another sexually transmitted disease

Published in Swiss medical weekly. 2003, vol. 133, no. 25-26, p. 353-9
Abstract During the past 30 years, there has been remarkable progress in our understanding of the pathogenesis of squamous cell carcinoma of the anus. It is now accepted that anal cancer is a sexually transmitted disease, which can be cured using a combination of chemo- and radiotherapy. The biology of anal cancer remains to be elucidated, as do the molecular mechanisms involved in resistance to chemoradiation. The contribution of HIV infection to tumour progression currently represents an area of intensive investigation. Finally, the growing numbers of AIDS patients who experience prolonged survival represent a population at risk. In the future, cytological screening of male homosexuals with an anal Papanicolaou test may help in identifying high-grade dysplasia and preventing anal cancer.
Keywords Acquired Immunodeficiency Syndrome/epidemiology/transmissionAnus Neoplasms/epidemiology/pathology/prevention & control/virologyCarcinoma, Squamous Cell/epidemiology/pathology/prevention & control/virologyComorbidityDisease Transmission, Infectious/prevention & controlFemaleHumansMaleMass Screening/methodsNeoplasm StagingPapanicolaou TestPapillomavirus Infections/epidemiology/transmissionSexually Transmitted Diseases, Viral/epidemiology/transmissionVaginal Smears/methods
PMID: 12947531
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Research groups Chirurgie viscérale (104)
Chirurgie viscérale (HUG)
(ISO format)
GERVAZ, Pascal et al. Squamous cell carcinoma of the anus: another sexually transmitted disease. In: Schweizerische medizinische Wochenschrift, 2003, vol. 133, n° 25-26, p. 353-9. doi: 10.2003/25/smw-10225 https://archive-ouverte.unige.ch/unige:45071

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Deposited on : 2015-01-13

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