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Title

Spleen transplantation in miniature swine: surgical technique and results in major histocompatibility complex-matched donor and recipient pairs

Authors
Gollackner, B
Dor, F J M F
Knosalla, C
Duggan, M
Huang, C A
Houser, S L
Sachs, D H
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Published in Transplantation. 2003, vol. 75, no. 11, p. 1799-806
Abstract Spleen transplantation (Tx) between some strains of rodents can lead to donor-specific tolerance either spontaneously or after a short course of immunosuppression. This study developed a surgical technique for spleen Tx in miniature swine to investigate its immunologic impact in a large animal model.
Keywords AnimalsBiopsyCyclosporine/pharmacologyFlow CytometryGraft Rejection/mortality/pathologyHematopoietic Stem Cells/cytologyHistocompatibility TestingImmunosuppressive Agents/pharmacologyMajor Histocompatibility Complex/immunologyPostoperative ComplicationsSkin Transplantation/immunologySpleen/pathology/transplantationSplenectomy/methodsSwine, MiniatureTissue DonorsTransplantation Chimera
Identifiers
PMID: 12811237
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Structures
Research group Cultures cellulaires et transplantations (519)
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GOLLACKNER, B et al. Spleen transplantation in miniature swine: surgical technique and results in major histocompatibility complex-matched donor and recipient pairs. In: Transplantation, 2003, vol. 75, n° 11, p. 1799-806. https://archive-ouverte.unige.ch/unige:45065

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Deposited on : 2015-01-13

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