Scientific article
English

Spleen transplantation in miniature swine: surgical technique and results in major histocompatibility complex-matched donor and recipient pairs

Published inTransplantation, vol. 75, no. 11, p. 1799-1806
Publication date2003
Abstract

Spleen transplantation (Tx) between some strains of rodents can lead to donor-specific tolerance either spontaneously or after a short course of immunosuppression. This study developed a surgical technique for spleen Tx in miniature swine to investigate its immunologic impact in a large animal model.

Keywords
  • Animals
  • Biopsy
  • Cyclosporine/pharmacology
  • Flow Cytometry
  • Graft Rejection/mortality/pathology
  • Hematopoietic Stem Cells/cytology
  • Histocompatibility Testing
  • Immunosuppressive Agents/pharmacology
  • Major Histocompatibility Complex/immunology
  • Postoperative Complications
  • Skin Transplantation/immunology
  • Spleen/pathology/transplantation
  • Splenectomy/methods
  • Swine, Miniature
  • Tissue Donors
  • Transplantation Chimera
Citation (ISO format)
GOLLACKNER, B et al. Spleen transplantation in miniature swine: surgical technique and results in major histocompatibility complex-matched donor and recipient pairs. In: Transplantation, 2003, vol. 75, n° 11, p. 1799–1806. doi: 10.1097/01.TP.0000063220.19441.5C
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
Journal ISSN0041-1337
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