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Scientific article
French

Neurodégénérescence et maladies cérébrovasculaires: coïncidence ou causalité ?

Published inRevue médicale suisse, vol. 2, no. 64, p. 1180-1184
Publication date2006
Abstract

Neurodegenerative and cerebrovascular diseases have been related for more than a century. Epidemiological data show that main vascular risk factors are also risk factors for Alzheimer disease. Experimental evidences demonstrate that some of those risk factors accelerate the progress of Alzheimer lesions, mainly by acting on the amyloid cascade. Recent advances in understanding the basic mechanisms of CADASIL and familial amyloid angiopathy reveal that these forms of vascular dementias are degenerative disease of brain vessels. Modern neuroimaging techniques will allow to better understand relations between symptomatic strokes, silent infarcts, leukoaraiosis, microbleeds and degenerative pathology before the stage of dementia.

Keywords
  • Cerebrovascular Disorders/complications
  • Humans
  • Neurodegenerative Diseases/etiology
  • Risk Factors
Citation (ISO format)
ASSAL, Frédéric et al. Neurodégénérescence et maladies cérébrovasculaires: coïncidence ou causalité ? In: Revue médicale suisse, 2006, vol. 2, n° 64, p. 1180–1184.
Identifiers
ISSN of the journal1660-9379
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