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Dose-dense cisplatin-based chemotherapy and surgery for children with high-risk hepatoblastoma (SIOPEL-4): a prospective, single-arm, feasibility study

Collaborateurs/tricesOzsahin, Ayse Hulya
Publié dansLancet oncology, vol. 14, no. 9, p. 834-842
Date de publication2013
Résumé

The objective of this study was to establish the efficacy and safety of a new treatment regimen consisting of dose-dense cisplatin-based chemotherapy and radical surgery in children with high-risk hepatoblastoma.

Mots-clés
  • Adolescent
  • Antineoplastic Combined Chemotherapy Protocols/therapeutic use
  • Child
  • Child, Preschool
  • Cisplatin/administration & dosage
  • Combined Modality Therapy
  • Dose-Response Relationship, Drug
  • Doxorubicin/administration & dosage
  • Feasibility Studies
  • Female
  • Follow-Up Studies
  • Hepatectomy
  • Hepatoblastoma/mortality/pathology/therapy
  • Humans
  • Liver Neoplasms/mortality/pathology/therapy
  • Lung Neoplasms/mortality/secondary/therapy
  • Male
  • Prognosis
  • Prospective Studies
  • Survival Rate
Citation (format ISO)
ZSIROS, József et al. Dose-dense cisplatin-based chemotherapy and surgery for children with high-risk hepatoblastoma (SIOPEL-4): a prospective, single-arm, feasibility study. In: Lancet oncology, 2013, vol. 14, n° 9, p. 834–842. doi: 10.1016/S1470-2045(13)70272-9
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Article (Published version)
accessLevelRestricted
Identifiants
ISSN du journal1470-2045
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Informations techniques

Création09/09/2014 15:14:00
Première validation09/09/2014 15:14:00
Heure de mise à jour14/03/2023 22:36:32
Changement de statut14/03/2023 22:36:31
Dernière indexation16/01/2024 15:38:06
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