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Title

Dose-dense cisplatin-based chemotherapy and surgery for children with high-risk hepatoblastoma (SIOPEL-4): a prospective, single-arm, feasibility study

Authors
Zsiros, József
Brugieres, Laurence
Brock, Penelope
Roebuck, Derek
Maibach, Rudolf
Zimmermann, Arthur
Childs, Margaret
Pariente, Daniele
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CollaborationWith : Ozsahin, Ayse Hulya
Published in The Lancet Oncology. 2013, vol. 14, no. 9, p. 834-42
Abstract The objective of this study was to establish the efficacy and safety of a new treatment regimen consisting of dose-dense cisplatin-based chemotherapy and radical surgery in children with high-risk hepatoblastoma.
Keywords AdolescentAntineoplastic Combined Chemotherapy Protocols/therapeutic useChildChild, PreschoolCisplatin/administration & dosageCombined Modality TherapyDose-Response Relationship, DrugDoxorubicin/administration & dosageFeasibility StudiesFemaleFollow-Up StudiesHepatectomyHepatoblastoma/mortality/pathology/therapyHumansLiver Neoplasms/mortality/pathology/therapyLung Neoplasms/mortality/secondary/therapyMalePrognosisProspective StudiesSurvival Rate
Identifiers
PMID: 23831416
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Research group Plateforme d'oncologie et d'hématologie pédiatrique (907)
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ZSIROS, József et al. Dose-dense cisplatin-based chemotherapy and surgery for children with high-risk hepatoblastoma (SIOPEL-4): a prospective, single-arm, feasibility study. In: The Lancet Oncology, 2013, vol. 14, n° 9, p. 834-42. doi: 10.1016/S1470-2045(13)70272-9 https://archive-ouverte.unige.ch/unige:44657

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Deposited on : 2015-01-07

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