Trends in incidence of breast cancer among women under 40 in seven European countries: a GRELL cooperative study

Leclère, Brice; Molinié, Florence; Trétarre, Brigitte; Stracci, Fabrizio; Daubisse-Marliac, Laetitia; Colonna, Marc; GRELL Collaborative Study

doi:10.1016/j.canep.2013.05.001

Scientific article

English

Trends in incidence of breast cancer among women under 40 in seven European countries: a GRELL cooperative study

Contributors

Leclère, Brice; Molinié, Florence; Trétarre, Brigitte; Stracci, Fabrizio; Daubisse-Marliac, Laetitia; Colonna, Marc; GRELL Collaborative Study

Collaborators

Usel, Massimo; Rapiti Aylward, Elisabetta

Published in

Cancer epidemiology, vol. 37, no. 5, p. 544-549

Publication date

2013

Abstract

Young women are not usually screened for breast cancer (BC). The trends in incidence in this population may better reflect changes in risk factors. However, studies on this subject are scarce and heterogeneous. The aim of this study was to describe the trends in incidence of BC in women under 40 from 1990 to 2008, using pooled European data. Thirty-seven European population-based cancer registries from Belgium, Bulgaria, France, Italy, Portugal, Spain and Switzerland participated in this study. World age-standardized incidence rates were first analyzed graphically and then using a Poisson regression model, in order to estimate average annual percent changes (AAPCs). The overall incidence rate of BC in the area covered increased linearly during the study period by 1.19% (0.93; 1.46) on average per year. This increase varied between countries from 0.20% (-0.53; 0.64) in Bulgaria to 2.68% (1.97; 3.40) in Portugal. In Italy, after a significant rise of 2.33% (1.14; 3.54) per year, BC incidence began decreasing in 2002 by -2.30% (-4.07; -0.50) yearly. The rise in incidence was greater for women under 35 and for ductal carcinomas. This increase can be due to a rise in risk factors and/or changes in diagnosis and surveillance practices, but we could not clearly distinguish between these two non-exclusive explanations.

Keywords

Adult
Age Factors
Breast Neoplasms/epidemiology
Europe/epidemiology
Female
Humans
Incidence
Registries

UNIGE affiliation entities

Faculté de médecine / Section de médecine clinique / Département de santé et médecine communautaires / Registre genevois des tumeurs

UNIGE research groups

Citation (ISO format)

LECLÈRE, Brice et al. Trends in incidence of breast cancer among women under 40 in seven European countries: a GRELL cooperative study. In: Cancer epidemiology, 2013, vol. 37, n° 5, p. 544–549. doi: 10.1016/j.canep.2013.05.001

Article (Published version)

Identifiers

PID : unige:44646
DOI : 10.1016/j.canep.2013.05.001
PMID : 23768969

Journal ISSN

1877-7821

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16/12/2014 13:39:00

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16/12/2014 13:39:00

Update

13/10/2025 21:58:32

Status update

14/03/2023 22:36:17

Last indexation

10/11/2026 17:14:35

Trends in incidence of breast cancer among women under 40 in seven European countries: a GRELL cooperative study

Contributors

Collaborators

Published in

Publication date

Abstract

Keywords

UNIGE affiliation entities

UNIGE research groups

Citation (ISO format)

Main files (1)

Identifiers

Journal ISSN

Technical informations

Creation

First validation

Update

Status update

Last indexation