Scientific article

L'état de mal résistant aux antiépileptiques

Published inClinical neurophysiology, vol. 30, no. 3, p. 139-145
Publication date2000

Refractory epileptic state (RES) is defined by severe seizures that are resistant to antiepileptic drug treatment. Diagnostic errors such as pseudo-seizures and encephalopathies with triphasic waves must be distinguished at an early stage from cases of RES. The latter are symptomatic of a focal brain lesion or severe systemic disease, most frequently metabolic in origin. The treatment of such conditions is aimed at correction of the underlying cause. A nosographic issue that is still a subject of discussion and which requires further study, i.e., PLEDS, will also be discussed in this article.

  • Anticonvulsants/therapeutic use
  • Drug Resistance
  • Humans
  • Status Epilepticus/diagnosis/drug therapy/etiology
Citation (ISO format)
ASSAL, Frédéric, COEYTAUX, Alessandra Cécile Maria, JALLON, Pierre-Marie. L’état de mal résistant aux antiépileptiques. In: Clinical neurophysiology, 2000, vol. 30, n° 3, p. 139–145. doi: 10.1016/S0987-7053(00)00201-X
Main files (1)
Article (Published version)
ISSN of the journal1388-2457

Technical informations

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