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Scientific article
English

Isotope specific resolution recovery image reconstruction in high resolution PET imaging

Published inMedical physics, vol. 41, no. 5, 052503
Publication date2014
Abstract

Measuring and incorporating a scanner-specific point spread function (PSF) within image reconstruction has been shown to improve spatial resolution in PET. However, due to the short half-life of clinically used isotopes, other long-lived isotopes not used in clinical practice are used to perform the PSF measurements. As such, non-optimal PSF models that do not correspond to those needed for the data to be reconstructed are used within resolution modeling (RM) image reconstruction, usually underestimating the true PSF owing to the difference in positron range. In high resolution brain and preclinical imaging, this effect is of particular importance since the PSFs become more positron range limited and isotope-specific PSFs can help maximize the performance benefit from using resolution recovery image reconstruction algorithms.

Keywords
  • Algorithms
  • Brain Neoplasms/radionuclide imaging
  • Carbon Radioisotopes/diagnostic use
  • Feasibility Studies
  • Fluorine Radioisotopes/diagnostic use
  • Head/radionuclide imaging
  • Humans
  • Image Processing, Computer-Assisted/methods
  • Oligodendroglioma/radionuclide imaging
  • Phantoms, Imaging
  • Positron-Emission Tomography/instrumentation/methods
  • Radiopharmaceuticals/diagnostic use
Citation (ISO format)
KOTASIDIS, Fotis et al. Isotope specific resolution recovery image reconstruction in high resolution PET imaging. In: Medical physics, 2014, vol. 41, n° 5, p. 052503. doi: 10.1118/1.4870985
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Article (Published version)
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ISSN of the journal0094-2405
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Creation19.12.2014 14:27:00
First validation19.12.2014 14:27:00
Update time14.03.2023 22:34:57
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