Isotope specific resolution recovery image reconstruction in high resolution PET imaging

Kotasidis, Fotis; Angelis, Georgios I; Anton-Rodriguez, Jose; Matthews, Julian C; Reader, Andrew J; Zaidi, Habib

doi:10.1118/1.4870985

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Title		Isotope specific resolution recovery image reconstruction in high resolution PET imaging
Authors		Kotasidis, Fotis Angelis, Georgios I Anton-Rodriguez, Jose Matthews, Julian C Reader, Andrew J Zaidi, Habib
Published in		Medical physics. 2014, vol. 41, no. 5, 052503
Abstract		Measuring and incorporating a scanner-specific point spread function (PSF) within image reconstruction has been shown to improve spatial resolution in PET. However, due to the short half-life of clinically used isotopes, other long-lived isotopes not used in clinical practice are used to perform the PSF measurements. As such, non-optimal PSF models that do not correspond to those needed for the data to be reconstructed are used within resolution modeling (RM) image reconstruction, usually underestimating the true PSF owing to the difference in positron range. In high resolution brain and preclinical imaging, this effect is of particular importance since the PSFs become more positron range limited and isotope-specific PSFs can help maximize the performance benefit from using resolution recovery image reconstruction algorithms.
Keywords		Algorithms — Brain Neoplasms/radionuclide imaging — Carbon Radioisotopes/diagnostic use — Feasibility Studies — Fluorine Radioisotopes/diagnostic use — Head/radionuclide imaging — Humans — Image Processing, Computer-Assisted/methods — Oligodendroglioma/radionuclide imaging — Phantoms, Imaging — Positron-Emission Tomography/instrumentation/methods — Radiopharmaceuticals/diagnostic use
Identifiers		DOI: 10.1118/1.4870985 PMID: 24784400
Full text		Article (Published version) (1.7 MB) - Limited access to UNIGE
Structures		Faculté de médecine / Section de médecine clinique / Département de radiologie et informatique médicale
Research group		Imagerie Médicale (TEP et TEMP) (542)
Project		Swiss National Science Foundation: 31003A_149957
Citation (ISO format)		KOTASIDIS, Fotis et al. Isotope specific resolution recovery image reconstruction in high resolution PET imaging. In: Medical physics, 2014, vol. 41, n° 5, p. 052503. doi: 10.1118/1.4870985 https://archive-ouverte.unige.ch/unige:44517