Prevalence of nasal colonization with methicillin-resistant Staphylococcus aureus (MRSA) in children a multicenter cross-sectional study

Heininger, Ulrich; Datta, Florence; Gervaix, Alain; Schaad, Urs B; Berger, Christoph; Vaudaux, Bernard; Aebi, Christoph; Hitzler, Michael; Kind, Christian; Gnehm, Hanspeter E; Frei, Reno; Myers, Catherine Jayne; Posfay Barbe, Klara

doi:10.1097/INF.0b013e31804d244a

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Title		Prevalence of nasal colonization with methicillin-resistant Staphylococcus aureus (MRSA) in children a multicenter cross-sectional study
Authors		Heininger, Ulrich Datta, Florence Gervaix, Alain Schaad, Urs B Berger, Christoph Vaudaux, Bernard Aebi, Christoph Hitzler, Michael Kind, Christian Gnehm, Hanspeter E Frei, Reno Myers, Catherine Jayne Posfay Barbe, Klara show all authors [1 - 13]
Published in		Pediatric Infectious Disease Journal. 2007, vol. 26, no. 6, p. 544-6
Abstract		In this cross-sectional multicenter study, we determined the rate of nasal carriage of methicillin-resistant Staphylococcus aureus (MRSA) in children admitted to 9 training hospitals in Switzerland during 1 month. From 1337 patients, 1363 nasal swabs were obtained (mean age 6.1 years, median 4.7 years, interquartile range 1.3-10.4 years) and 562 (41.3%) grew S. aureus. Only one isolate was MRSA (0.18%) which encoded mecA and femA genes as well as SCCmec type IV, whereas Panton-Valentine leukocidin (PVL) was absent.
Keywords		Adolescent — Bacterial Proteins/genetics — Bacterial Toxins/genetics — Carrier State/epidemiology/microbiology — Child — Child, Preschool — Cross-Sectional Studies — DNA, Bacterial/genetics — Exotoxins/genetics — Female — Hospitalization — Hospitals, Teaching — Humans — Infant — Leukocidins/genetics — Male — Methicillin Resistance — Nasal Cavity/microbiology — Prevalence — Staphylococcal Infections/epidemiology/microbiology — Staphylococcus aureus/drug effects/isolation & purification — Switzerland/epidemiology
Identifiers		DOI: 10.1097/INF.0b013e31804d244a PMID: 17529877
Full text		Article (Published version) (699 Kb) - Limited access to UNIGE
Structures		Faculté de médecine / Section de médecine clinique / Département de pédiatrie, gynécologie et obstétrique
Research groups		Etiologie des pneumonies et marqueurs inflammatoires chez l'enfant fébrile (183) Recherche en infectiologie pédiatrique et en pédiatrie générale (853)
Citation (ISO format)		HEININGER, Ulrich et al. Prevalence of nasal colonization with methicillin-resistant Staphylococcus aureus (MRSA) in children a multicenter cross-sectional study. In: Pediatric Infectious Disease Journal, 2007, vol. 26, n° 6, p. 544-6. doi: 10.1097/INF.0b013e31804d244a https://archive-ouverte.unige.ch/unige:43988